Current News

P.A. Technologies Awarded 2007 SBS Best Poster Award for a poster titled “Template-Directed Self-Assembly Enhances RTK Catalytic Domain Function”.

Please contact us for a PDF of this poster- click here.

2009 Events

• February 19-20 - 6^th Annual Cancer Drugs Research and Development conference, Philadelphia, PA.  Edward Esposito will give a talk titled:  “Template-Directed-Assembly of RTK TK Domains Restores Biologically-Relevant Function”

• April 6-10 – Fifth Annual Protein Engineering Summit, Boston, MA.   Stephen Zolnay, Vice President of Business Development, P.A. Technologies (in conjunction with BlueSky Biotech) will give a talk titled: “Template-Directed-Assembly of RTK TK Domains Restores Biologically-Relevant Function”

2008 Events

• April 6-10 - Come see us at the SBS meeting in St. Louis, MO. Booth 1720

• Come see us at booth 812 at the 2008 DDT show in Boston, MA

2007 Events

• August 11-17 - FASEB conference - Tucson, AZ

• December 17th - Millipore Launches BioFormTM Technology, developed by P. A. Technologies, LLC

Check back soon for updates!

Publications & Presentations

1. Esposito, E. A., Shrout, A. L., Weis, R. M.  Template-directed Self-Assembly Enhances RTK Catalytic Domain Function.  J. Biomol. Screen. 2008, 13, 810-816.
    

2. Besschetnova, T.Y., Montefusco, D.J., Asinas, A. E., Shrout, A.L., Antommattei, F. M., Weis, R.M. Receptor density balances signal stimulation and attenuation in membrane-assembled complexes of bacterial chemotaxis signaling proteins.  Proc. Nat. Acad. Sci. 2008, 105, 12289-12294.
    

3. Shrout, A. L., Esposito, E. A., Weis, R. M.  Template-directed Assembly of Signaling Proteins: A Novel Drug Screening and Research Tool.  Chem. Biol. Drug Des. 2008, 71, 278-281.
    

4. Montefusco, D.J., Shrout, A.L., Besschetnova, T.Y., Weis, R.M. Formation and Activity of Template-Assembled Receptor Signaling Complexes.  Langmuir. 2007, 23, 3280 - 3289.
    

5. Abdalin E. Asinas and Robert M. Weis. Competitive and Cooperative Interactions in Receptor Signaling Complexes. J. Biol. Chem., 2006; 281: 30512 - 30523.
    

6. Shrout, A.L., Montefusco, D.J., Weis, R.M..  Template-Directed Assembly of Receptor Signaling Complexes.  Biochemistry. 2003, 42, 13379-13385.